Is Zyrtec (cetirizine) Safe for Cats?
Caution — Zyrtec (cetirizine) can be risky for cats.
Zyrtec (cetirizine) isn't classed as outright toxic, but it warrants caution around cats — Plain cetirizine is generally well tolerated off-label, BUT Zyrtec-D contains pseudoephedrine (toxic) and some liquids contain propylene glycol.. When in doubt, keep it out of reach and ask your veterinarian.
| Category | Medicine |
|---|---|
| Also known as | zyrtec, cetirizine, antihistamine |
Signs to watch for in cats
Plain: occasional drowsiness, drooling, mild GI upset. The 'D' form: fast heart rate, agitation, tremors, seizures. Use only under vet direction; never the 'D' or syrup form.
If your cat may have been exposed to Zyrtec (cetirizine):
- Don't wait for symptoms; don't induce vomiting unless a professional tells you to.
- Note what and how much, and take any packaging with you.
- Call your vet or a 24/7 line now — Pet Poison Helpline 855-764-7661 · ASPCA 888-426-4435.
Cat-safe alternatives
Browse all Medicine for cats · or check another item.
Source: VCA Hospitals; Merck Vet Manual ↗
Frequently asked questions
Is Zyrtec (cetirizine) safe for cats?
Zyrtec (cetirizine) is best treated with caution — it isn't classed as toxic but can cause problems for cats in some forms or amounts.
What are the symptoms if a cat is exposed to Zyrtec (cetirizine)?
Reported signs include: Plain: occasional drowsiness, drooling, mild GI upset. The 'D' form: fast heart rate, agitation, tremors, seizures. Use only under vet direction; never the 'D' or syrup form.
What should I do if my cat ate Zyrtec (cetirizine)?
Contact your vet or a 24/7 animal poison line right away: Pet Poison Helpline (855-764-7661) or ASPCA Animal Poison Control (888-426-4435).